Sistematização das artérias da base do encéfalo em nutria (Myocastor coypus)
Azambuja, Rodrigo Cavalcanti deGoltz, Laura VerCampos, Rui
Background: The nutria (Myocastor coypus) is a medium-size, semi-aquatic rodent, valued in skin and meat industry. The brain circulation has been well studied in rodents but not in nutria. To understand and compare the phylogenetic development of the arteries of the base of the brain in rodents, this paper aims to describe and systematize these arteries, establishing a standard model and its main variations in nutria.Materials, Methods & Results: Following approval by the Ethics Committee of Federal University of Rio Grande do Sul, thirty nutrias from a commercial establishment authorized by Brazilian Institute of Environment and Natural Resources (IBAMA) were studied. For euthanasia, was applied heparin (10000 U.I for animal), intraperitoneally, and after thirty minutes the animals ware sedated with acepromazine (0.5 mg/kg) and meperidine (20 mg/kg), intramuscularly. After sedation, they were euthanized with thiopental sodium (120 mg/kg) and lidocaine (10 mg/mL), intraperitoneally. The heart was accessed, the cardiac apex was sectioned, the aorta was cannulated via the left ventricle and clamped close to the diaphragm, and the arterial system was washed with saline solution and filled with latex. The animals were submerged in water for latex polymerization, the trunk was sectioned, the skin removed and a bony window was opened in the skull vault. The pieces were fixed in formaldehyde. The brains were removed, and schematic drawings of the arteries from the base of the brain were made for elaboration of the results. The nutrias brain was vascularized by the vertebro-basilar system. The terminal branches of the right and left vertebral artery were anastomosed on the ventral surface of the medulla oblongata, forming the basilar artery, and caudally the ventral spinal artery.[...](AU)
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