VETINDEX

Periódicos Brasileiros em Medicina Veterinária e Zootecnia

p. 995-1000

Canine coronavirus (CCoV) in dogs vaccinated and unvaccinated domiciliated in Pelotas, RS, Brazil

Caetano de Castro, ClarissaMaria Johann, JucianeFonseca Finger, PaulaFreitas Nunes, CristinaD'Avila Vargas, GilbertoFischer, Gefersonde Oliveira Hübner, Silvia

Canine coronavirus (CCoV) has been reported causing enteric disease mainly in young pups. In this study, to investigate immunity and exposure to CCoV, was estimated the frequency of serum antibodies to CCoV in 121 dogs in the Pelotas, South of Brazil, by serum neutralization test (SN): 22 had not been vaccinated, 69 had been vaccinated at least once, and 30 had unknown vaccination history. Antibodies were present in 47,8% (33/69) of the vaccinated dogs, in 45,5% (10/22) of the unvaccinated, and in 43,3% (13/30) of the dogs with unknown historical vaccination. There was no significant relationship between these antibodies and sex, age, habitat, and season of collection. The results proved the circulation of the CCoV among this dog population and indicated that the infection affects a significant group of animals. The large proportion of seronegative vaccinated dogs indicates failure of CCoV vaccine in inducing neutralizing antibodies, suggesting that immunizations to CCoV should be reevaluated. The authors indicate the need for further studies in order to evaluate the impact of the infection caused by CCoV, as well as to propose and evaluate preventive measures.

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